Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC109202378Tripartite motif containing 25. (668 aa)    
Predicted Functional Partners:
LOC100702954
Interferon regulatory factor 3.
   
 0.697
ifih1
Interferon induced with helicase C domain 1.
   
 0.625
LOC102082729
Uncharacterized protein.
     
  0.612
LOC100708566
Uncharacterized protein.
     
  0.612
LOC100703599
Tripartite motif containing 107.
     
  0.612
LOC100705925
E3 ubiquitin/ISG15 ligase TRIM25 isoform X2.
     
  0.612
irf5
Interferon regulatory factor 5.
    
 0.585
DTX1
Deltex E3 ubiquitin ligase 1.
      
 0.575
dhx58
Probable ATP-dependent RNA helicase DHX58.
   
 0.563
tbk1
TANK-binding kinase 1.
   
 0.548
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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