Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmem39aTransmembrane protein 39A. (493 aa)    
Predicted Functional Partners:
pld6
Phospholipase D family, member 6.
      
 0.576
sec63
SEC63 homolog, protein translocation regulator.
      
 0.563
ENSONIP00000037107
annotation not available
      
 0.522
clec16a
C-type lectin domain containing 16A.
      
 0.476
kif21b
Kinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.476
LOC100707170
Receptor expression-enhancing protein.
      
 0.446
LOC100696294
Receptor expression-enhancing protein.
      
 0.446
hgh1
HGH1 homolog (S. cerevisiae).
      
 0.429
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
      
 0.427
uba5
Ubiquitin-like modifier activating enzyme 5.
   
  
 0.421
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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