STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1064 aa)    
Predicted Functional Partners:
ENSONIP00000000682
Intersectin 2a.
    
  0.968
I3KKD0_ORENI
Intersectin 2b.
    
  0.968
ddx21
DEAD (Asp-Glu-Ala-Asp) box helicase 21.
   
 0.876
ddx1
DEAD (Asp-Glu-Ala-Asp) box helicase 1.
   
 0.871
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.838
itsn1
Intersectin 1 (SH3 domain protein).
    
  0.792
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.784
ddx56
DEAD (Asp-Glu-Ala-Asp) box helicase 56.
   
 0.777
LOC100701316
UTP14C small subunit processome component.
   
 0.775
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.755
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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