Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PM20D2Peptidase M20 domain-containing protein 2; Belongs to the peptidase M20A family. (423 aa)    
Predicted Functional Partners:
LOC100711605
Malate synthase-like.
   
 0.899
pgrmc2
Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family.
      
 0.783
Mdn1
Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.
    
 
 0.698
ube2j1
Ubiquitin-conjugating enzyme E2, J1.
    
 
 0.635
nip7
60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.
      
 0.625
setd2
SET domain containing 2, histone lysine methyltransferase.
    
   0.582
Ankrd6
Ankyrin repeat domain 6b.
   
  
 0.580
coq5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).
     
 0.528
allc
Allantoicase.
   
 
 0.506
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1.
    
 
 0.503
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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