Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NT5E5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. (584 aa)    
Predicted Functional Partners:
LOC100702364
GMP reductase 2.
   
 0.922
LOC100706644
Phosphodiesterase.
     
 0.922
pde6c
Phosphodiesterase.
     
 0.922
gmpr
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
   
 0.922
I3J8W3_ORENI
Phosphodiesterase.
     
 0.922
ada
Adenosine deaminase.
    
 0.920
aprt
Adenine phosphoribosyltransferase.
    
 0.905
entpd3
Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.
     
 0.903
LOC100709923
Uncharacterized protein.
  
 
 0.902
I3JFA0_ORENI
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
  
 
 0.902
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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