STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPM1LProtein phosphatase, Mg2+/Mn2+ dependent 1L. (357 aa)    
Predicted Functional Partners:
bckdhb
Branched chain keto acid dehydrogenase E1 subunit beta.
   
 0.693
dbt
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 0.663
bckdha
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 0.659
vapb
VAMP (vesicle-associated membrane protein)-associated protein B and C.
    
 0.558
vapa
VAMP (vesicle-associated membrane protein)-associated protein A, like.
    
 0.558
LOC100711919
MSP domain-containing protein.
    
 0.544
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.527
tab2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.527
LOC102081483
Ubiquitin-conjugating enzyme E2 variant 1.
     
 0.521
I3IYX1_ORENI
Arylalkylamine N-acetyltransferase 2.
    
   0.520
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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