STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
map3k10Mitogen-activated protein kinase kinase kinase 10. (1049 aa)    
Predicted Functional Partners:
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.670
cd247
T-cell surface glycoprotein CD3 zeta chain.
   
 0.663
tab1
TGF-beta activated kinase 1/MAP3K7 binding protein 1.
   
 0.658
tradd
Tnfrsf1a-associated via death domain.
   
 0.611
mib2
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.611
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.609
tab2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.609
Fadd
Uncharacterized protein.
   
 0.587
LOC100712348
Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.553
LOC100699741
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.553
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.