Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
itgb1Integrin beta; Belongs to the integrin beta chain family. (813 aa)    
Predicted Functional Partners:
itga2
Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2; Belongs to the integrin alpha chain family.
   
 0.981
itga4
Integrin alpha 4; Belongs to the integrin alpha chain family.
   
 0.978
itga9
Integrin, alpha 9; Belongs to the integrin alpha chain family.
   
 0.978
itga1
Integrin, alpha 1; Belongs to the integrin alpha chain family.
   
 0.978
ITGA7
Integrin subunit alpha 7; Belongs to the integrin alpha chain family.
   
 0.977
LOC100705213
Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.
   
 0.975
LOC100711808
Talin 1.
   
 0.975
itga3
Integrin, alpha 3b; Belongs to the integrin alpha chain family.
   
 0.975
LOC100704409
Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.
   
 0.970
itga8
Integrin, alpha 8; Belongs to the integrin alpha chain family.
   
 0.970
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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