Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
LOC100700935ADAM metallopeptidase domain 17a. (851 aa)    
Predicted Functional Partners:
LOC100534578
Tumor necrosis factor b (TNF superfamily, member 2).
    
 0.952
LOC100691361
Heparin-binding EGF-like growth factor a.
    
 0.909
LOC100698688
Notch receptor 2.
    
 0.908
LOC100696073
Notch receptor 3.
    
 0.907
ENSONIP00000032417
Uncharacterized protein LOC100702023 isoform X1.
   
 
 0.902
LOC100703553
Notch receptor 1a.
    
 0.889
notch1
Notch receptor 1b.
    
 0.889
LOC100705478
C-mer proto-oncogene tyrosine kinase a.
    
 0.883
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 
 0.879
RHBDF2
Rhomboid 5 homolog 2.
    
 0.870
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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