Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
crklV-crk avian sarcoma virus CT10 oncogene homolog-like. (310 aa)    
Predicted Functional Partners:
Bcar1
BCAR1 scaffold protein, Cas family member.
    
 0.974
abl1
Tyrosine-protein kinase.
    
 0.974
abl2
Tyrosine-protein kinase.
    
 0.974
LOC100712315
Uncharacterized protein.
    
 0.968
rapgef1
Rap guanine nucleotide exchange factor (GEF) 1b.
    
 0.968
Dock1
Dedicator of cytokinesis 1; Belongs to the DOCK family.
    
 0.967
mapk10
Mitogen-activated protein kinase.
    
 0.960
dock5
Dedicator of cytokinesis 5; Belongs to the DOCK family.
    
 0.960
LOC100707394
PH domain-containing protein.
    
 0.955
I3JUL5_ORENI
GRB2-associated binding protein 1.
    
 0.955
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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