Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wdr53WD repeat domain 53. (386 aa)    
Predicted Functional Partners:
prpf3
PRP3 pre-mRNA processing factor 3 homolog (yeast).
   
 0.926
prpf31
PRP31 pre-mRNA processing factor 31 homolog (yeast).
   
 0.891
prpf6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae).
   
 0.856
prpf8
Pre-mRNA processing factor 8.
   
 0.838
snrnp200
Small nuclear ribonucleoprotein 200 (U5).
   
 0.838
eftud2
Elongation factor Tu GTP binding domain containing 2.
   
 0.827
snrpe
Small nuclear ribonucleoprotein E.
   
 0.819
SART1
Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.
   
 0.817
I3J129_ORENI
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 0.816
Lsm8
LSM8 homolog, U6 small nuclear RNA associated.
   
 0.806
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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