Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
bud23BUD23 rRNA methyltransferase and ribosome maturation factor. (282 aa)    
Predicted Functional Partners:
trmt112
tRNA methyltransferase subunit 11-2.
   
 0.996
Ltv1
LTV1 ribosome biogenesis factor.
   
 0.985
bysl
Bystin-like.
   
 0.979
nop14
NOP14 nucleolar protein homolog (yeast).
   
 
 0.971
tsr1
TSR1 ribosome maturation factor.
   
 0.964
nob1
RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family.
   
 0.963
pno1
Partner of NOB1 homolog.
   
 0.937
dimt1
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
   
 
 0.932
UBE2O
Ubiquitin conjugating enzyme E2 O.
    
   0.926
LOC100701316
UTP14C small subunit processome component.
   
 
 0.925
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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