STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
map4k2Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (868 aa)    
Predicted Functional Partners:
traf2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
  0.902
I3JW29_ORENI
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
  0.902
LOC100697642
Neurofibromin 2b (merlin).
    
 
 0.454
grb2
Growth factor receptor-bound protein 2b.
   
 
 0.423
LOC100710037
Growth factor receptor-bound protein 2-B isoform X1.
   
 
 0.421
LOC100710443
GRB2 related adaptor protein 2b.
   
 
 0.421
ENSONIP00000032932
annotation not available
   
 
 0.421
LOC100704732
Ras-related GTP binding A.
    
 
 0.404
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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