Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100710841BCR activator of RhoGEF and GTPase. (1381 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.960
abl1
Tyrosine-protein kinase.
    
 0.925
abl2
Tyrosine-protein kinase.
    
 0.870
LOC100696779
SHC (Src homology 2 domain containing) transforming protein 2.
     
 0.796
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.744
LOC100696389
Uncharacterized protein.
    
 0.744
LOC100705099
CRK proto-oncogene, adaptor protein.
    
 0.744
LOC100711123
Ankyrin repeat and SOCS box containing 3.
     
 0.716
LOC100692645
Uncharacterized protein.
    
 0.678
LOC100699525
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.678
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.