Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
I3J6Y0_ORENIUncharacterized protein; Belongs to the peptidase C14A family. (383 aa)    
Predicted Functional Partners:
LOC100693633
PYD and CARD domain containing.
   
 0.952
LOC100707066
Interleukin-1.
   
 0.930
LOC100702139
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.773
LOC109194206
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.736
I3KF49_ORENI
Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.706
gsdme
Gasdermin Eb.
    
 0.681
Fadd
Uncharacterized protein.
    
 0.673
appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
 0.653
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.653
LOC100693282
Interleukin-1.
    
 0.649
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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