Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ppcsPhosphopantothenoylcysteine synthetase. (320 aa)    
Predicted Functional Partners:
coasy
CoA synthase.
  
 0.991
pank4
Pantothenate kinase.
     
 0.963
ppcdc
Phosphopantothenoylcysteine decarboxylase.
    
 0.953
LOC100710057
Pantothenate kinase 2.
     
 0.939
LOC100705818
Pantothenate kinase 1a.
     
 0.939
kyat1
Kynurenine aminotransferase 1.
  
  0.923
kyat3
Kynurenine aminotransferase 3.
  
  0.923
cth
Cystathionase (cystathionine gamma-lyase), like.
   
 
 0.918
cdo1
Cysteine dioxygenase.
     
  0.916
LOC100705311
Aspartate aminotransferase.
    
  0.916
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.