pot1 protein (Oreochromis niloticus) - STRING interaction network

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[Homology]

Score

pot1

Protection of telomeres 1 homolog. (795 aa)

Predicted Functional Partners:

terf2ip

0.999

ENSONIP00000060527

0.999

ENSONIP00000021671

0.992

ENSONIP00000070132

0.992

stn1

0.990

tpp1

0.972

tert

0.961

LOC102083268

0.958

ten1

0.958

LOC100705733

0.958

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000021671	ENSONIP00000060527	ENSONIP00000021671	ENSONIP00000060527	Telomeric repeat-binding factor 2 isoform X1.	TERF1 (TRF1)-interacting nuclear factor 2.	0.992
ENSONIP00000021671	ENSONIP00000070132	ENSONIP00000021671	ENSONIP00000070132	Telomeric repeat-binding factor 2 isoform X1.	annotation not available	0.560
ENSONIP00000021671	LOC100705733	ENSONIP00000021671	ENSONIP00000058503	Telomeric repeat-binding factor 2 isoform X1.	CST complex subunit CTC1.	0.749
ENSONIP00000021671	LOC102083268	ENSONIP00000021671	ENSONIP00000027774	Telomeric repeat-binding factor 2 isoform X1.	CST complex subunit CTC1 isoform X1.	0.749
ENSONIP00000021671	pot1	ENSONIP00000021671	ENSONIP00000005037	Telomeric repeat-binding factor 2 isoform X1.	Protection of telomeres 1 homolog.	0.992
ENSONIP00000021671	stn1	ENSONIP00000021671	ENSONIP00000011218	Telomeric repeat-binding factor 2 isoform X1.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.719
ENSONIP00000021671	ten1	ENSONIP00000021671	ENSONIP00000048814	Telomeric repeat-binding factor 2 isoform X1.	TEN1 subunit of CST complex.	0.770
ENSONIP00000021671	terf2ip	ENSONIP00000021671	ENSONIP00000018014	Telomeric repeat-binding factor 2 isoform X1.	Uncharacterized protein.	0.994
ENSONIP00000021671	tert	ENSONIP00000021671	ENSONIP00000040184	Telomeric repeat-binding factor 2 isoform X1.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.646
ENSONIP00000060527	ENSONIP00000021671	ENSONIP00000060527	ENSONIP00000021671	TERF1 (TRF1)-interacting nuclear factor 2.	Telomeric repeat-binding factor 2 isoform X1.	0.992
ENSONIP00000060527	ENSONIP00000070132	ENSONIP00000060527	ENSONIP00000070132	TERF1 (TRF1)-interacting nuclear factor 2.	annotation not available	0.992
ENSONIP00000060527	LOC100705733	ENSONIP00000060527	ENSONIP00000058503	TERF1 (TRF1)-interacting nuclear factor 2.	CST complex subunit CTC1.	0.902
ENSONIP00000060527	LOC102083268	ENSONIP00000060527	ENSONIP00000027774	TERF1 (TRF1)-interacting nuclear factor 2.	CST complex subunit CTC1 isoform X1.	0.902
ENSONIP00000060527	pot1	ENSONIP00000060527	ENSONIP00000005037	TERF1 (TRF1)-interacting nuclear factor 2.	Protection of telomeres 1 homolog.	0.999
ENSONIP00000060527	stn1	ENSONIP00000060527	ENSONIP00000011218	TERF1 (TRF1)-interacting nuclear factor 2.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.821
ENSONIP00000060527	ten1	ENSONIP00000060527	ENSONIP00000048814	TERF1 (TRF1)-interacting nuclear factor 2.	TEN1 subunit of CST complex.	0.830
ENSONIP00000060527	terf2ip	ENSONIP00000060527	ENSONIP00000018014	TERF1 (TRF1)-interacting nuclear factor 2.	Uncharacterized protein.	0.999
ENSONIP00000060527	tert	ENSONIP00000060527	ENSONIP00000040184	TERF1 (TRF1)-interacting nuclear factor 2.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.891
ENSONIP00000060527	tpp1	ENSONIP00000060527	ENSONIP00000056403	TERF1 (TRF1)-interacting nuclear factor 2.	Tripeptidyl peptidase I.	0.723
ENSONIP00000070132	ENSONIP00000021671	ENSONIP00000070132	ENSONIP00000021671	annotation not available	Telomeric repeat-binding factor 2 isoform X1.	0.560