Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppp1r13lProtein phosphatase 1, regulatory subunit 13 like. (795 aa)    
Predicted Functional Partners:
p53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.984
yap1
Yes-associated protein 1.
    
 0.863
il10
Interleukin 10.
    
 0.797
ppp1cc
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
  0.794
LOC100706881
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
  0.794
LOC100691882
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
  0.794
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
  0.792
LOC100692170
Serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1.
    
  0.792
LOC109196021
Serine/threonine-protein phosphatase PP1-beta catalytic subunit.
    
  0.792
mapre1
Microtubule-associated protein, RP/EB family, member 1b.
    
   0.758
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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