Hmga2 protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

Hmga2

Uncharacterized protein. (132 aa)

Predicted Functional Partners:

xrcc6

0.956

parp1

0.913

ENSONIP00000021408

0.873

rb1

0.736

suox

0.722

lemd3

0.678

lin28b

0.662

chaf1a

0.654

msrb3

0.654

zfat

0.649

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000021408	Hmga2	ENSONIP00000021408	ENSONIP00000005064	High mobility group AT-hook 1a.	Uncharacterized protein.	0.873
ENSONIP00000021408	parp1	ENSONIP00000021408	ENSONIP00000074983	High mobility group AT-hook 1a.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.766
ENSONIP00000021408	rb1	ENSONIP00000021408	ENSONIP00000076566	High mobility group AT-hook 1a.	Retinoblastoma 1.	0.408
Hmga2	ENSONIP00000021408	ENSONIP00000005064	ENSONIP00000021408	Uncharacterized protein.	High mobility group AT-hook 1a.	0.873
Hmga2	chaf1a	ENSONIP00000005064	ENSONIP00000003223	Uncharacterized protein.	Chromatin assembly factor 1, subunit A (p150).	0.654
Hmga2	lemd3	ENSONIP00000005064	ENSONIP00000046686	Uncharacterized protein.	LEM domain containing 3.	0.678
Hmga2	lin28b	ENSONIP00000005064	ENSONIP00000018512	Uncharacterized protein.	Lin-28 homolog B (C. elegans).	0.662
Hmga2	msrb3	ENSONIP00000005064	ENSONIP00000079492	Uncharacterized protein.	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	0.654
Hmga2	parp1	ENSONIP00000005064	ENSONIP00000074983	Uncharacterized protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.913
Hmga2	rb1	ENSONIP00000005064	ENSONIP00000076566	Uncharacterized protein.	Retinoblastoma 1.	0.736
Hmga2	suox	ENSONIP00000005064	ENSONIP00000024166	Uncharacterized protein.	Sulfite oxidase.	0.722
Hmga2	xrcc6	ENSONIP00000005064	ENSONIP00000043248	Uncharacterized protein.	X-ray repair complementing defective repair in Chinese hamster cells 6.	0.956
Hmga2	zfat	ENSONIP00000005064	ENSONIP00000008843	Uncharacterized protein.	Uncharacterized protein.	0.649
chaf1a	Hmga2	ENSONIP00000003223	ENSONIP00000005064	Chromatin assembly factor 1, subunit A (p150).	Uncharacterized protein.	0.654
lemd3	Hmga2	ENSONIP00000046686	ENSONIP00000005064	LEM domain containing 3.	Uncharacterized protein.	0.678
lemd3	msrb3	ENSONIP00000046686	ENSONIP00000079492	LEM domain containing 3.	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	0.824
lin28b	Hmga2	ENSONIP00000018512	ENSONIP00000005064	Lin-28 homolog B (C. elegans).	Uncharacterized protein.	0.662
msrb3	Hmga2	ENSONIP00000079492	ENSONIP00000005064	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Uncharacterized protein.	0.654
msrb3	lemd3	ENSONIP00000079492	ENSONIP00000046686	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	LEM domain containing 3.	0.824
parp1	ENSONIP00000021408	ENSONIP00000074983	ENSONIP00000021408	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	High mobility group AT-hook 1a.	0.766