Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC100703896Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)    
Predicted Functional Partners:
LOC100711075
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.973
LOC100703259
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.
   
 0.958
LOC100706288
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1.
   
 0.958
drd2
Dopamine receptor D2a; Belongs to the G-protein coupled receptor 1 family.
    
  0.940
calcr
Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.
    
  0.940
drd3
Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.
    
  0.940
LOC100696010
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma.
     
 0.936
gper1
G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.935
LOC100699280
Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family.
    
 0.927
LOC100695984
Melanocortin 4 receptor.
    
 0.926
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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