Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Bcar1BCAR1 scaffold protein, Cas family member. (984 aa)    
Predicted Functional Partners:
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.974
LOC100696389
Uncharacterized protein.
    
 0.974
LOC100705099
CRK proto-oncogene, adaptor protein.
    
 0.974
I3JID5_ORENI
Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.956
I3J3T9_ORENI
Protein tyrosine kinase 2.
   
 0.956
LOC100706266
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.939
ENSONIP00000069782
Paxillin b.
    
 0.939
Itgb8
Integrin beta; Belongs to the integrin beta chain family.
    
 0.927
itgb1
Integrin beta; Belongs to the integrin beta chain family.
    
 0.924
LOC100692535
Integrin beta; Belongs to the integrin beta chain family.
    
 0.924
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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