Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
snx30Sorting nexin family member 30. (449 aa)    
Predicted Functional Partners:
LOC100711848
PX domain-containing protein.
   
 0.862
LOC100695030
Sorting nexin 4.
   
 0.862
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.855
bloc1s2
Biogenesis of lysosomal organelles complex-1, subunit 2.
    
 
 0.785
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.705
LOC100706230
Vesicle-associated membrane protein 1.
    
 0.681
ENSONIP00000050976
Vesicle-associated membrane protein 2.
    
 0.681
LOC100706223
Zgc:92912.
    
 0.681
snx6
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.671
snx5
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.671
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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