Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ercc1Excision repair cross-complementation group 1. (352 aa)    
Predicted Functional Partners:
xpa
Xeroderma pigmentosum, complementation group A.
    
 0.999
ercc4
Excision repair cross-complementation group 4.
   
 0.999
mus81
MUS81 structure-specific endonuclease subunit.
   
 0.997
fancm
Uncharacterized protein.
   
 0.997
Slx4
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).
   
 0.981
I3KHG4_ORENI
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).
   
 0.981
ercc3
Excision repair cross-complementation group 3.
     
 0.979
rad52
DNA repair and recombination protein RAD52.
    
 0.971
ercc2
Excision repair cross-complementation group 2.
     
 0.965
eme1
Essential meiotic structure-specific endonuclease 1.
    
 0.960
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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