Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100703081Uncharacterized protein. (1109 aa)    
Predicted Functional Partners:
cdc42
Cell division cycle 42.
    
 0.747
ENSONIP00000000682
Intersectin 2a.
   
 0.701
I3KKD0_ORENI
Intersectin 2b.
   
 0.701
itsn1
Intersectin 1 (SH3 domain protein).
   
 0.566
nckipsd
NCK interacting protein with SH3 domain.
    
 
 0.526
LOC100711529
Growth arrest specific 7.
    
 0.513
LOC100706459
Growth arrest-specific 7a.
    
 0.513
LOC100704372
Ras homolog family member F.
    
 0.501
grb2
Growth factor receptor-bound protein 2b.
    
 0.492
I3KK64_ORENI
Uncharacterized protein.
    
 0.484
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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