Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
zc3h18Zinc finger CCCH-type containing 18. (1138 aa)    
Predicted Functional Partners:
zcchc8
Zinc finger, CCHC domain containing 8.
    
 0.970
srrt
Serrate RNA effector molecule homolog (Arabidopsis).
   
 0.955
LOC100710359
Uncharacterized protein.
   
 0.955
prpf4b
Pre-mRNA processing factor 4Bb.
   
   0.937
sf3a2
Splicing factor 3a, subunit 2.
   
   0.925
NCBP1
Nuclear cap binding protein subunit 1.
   
 0.910
I3KNC8_ORENI
Uncharacterized protein.
   
   0.899
ENSONIP00000031680
Nuclear cap-binding protein subunit 2-like.
   
 0.890
ENSONIP00000046810
Nuclear cap-binding protein subunit 2-like.
   
 0.890
LOC100702413
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
   
 0.890
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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