Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SH3RF3SH3 domain containing ring finger 3. (840 aa)    
Predicted Functional Partners:
uxs1
UDP-glucuronate decarboxylase 1.
   
  
 0.914
sptlc1
Serine palmitoyltransferase, long chain base subunit 1.
      
 0.802
Sorl1
Sortilin-related receptor, L(DLR class) A repeats containing.
   
 0.743
asmtl
Acetylserotonin O-methyltransferase-like.
      
 0.704
LOC100704314
Zinc fingers and homeoboxes 3.
    
 
 0.675
akap17a
A kinase (PRKA) anchor protein 17A.
      
 0.672
gak
Cyclin G associated kinase.
   
 0.660
itgbl1
Integrin, beta-like 1.
     
 0.649
LOC102077550
BEN domain containing 5.
      
 0.637
I3KTJ2_ORENI
Rabaptin, RAB GTPase binding effector protein 2.
      
 0.625
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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