Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
sfi1SFI1 centrin binding protein. (1126 aa)    
Predicted Functional Partners:
LOC100689752
Centrin, EF-hand protein, 2.
    
 0.940
LOC100695822
Centrin 4.
    
 0.938
cetn3
Centrin 3.
    
 0.930
rbks
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
      
 0.868
I3KTG4_ORENI
Cramped chromatin regulator homolog 1.
      
 0.861
crppa
CDP-L-ribitol pyrophosphorylase A.
    
 0.843
Thap7
THAP domain-containing protein 7 isoform X7.
      
 0.764
nr0b2
Orphan nuclear receptor SHP.
      
 0.728
Crym
Crystallin, mu.
      
 0.726
cep76
Centrosomal protein 76.
     
 0.725
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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