Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
I3J919_ORENISerotransferrin; Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate. (728 aa)    
Predicted Functional Partners:
LOC100702695
Transferrin receptor 1b.
  
 0.707
epo
Erythropoietin; Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Belongs to the EPO/TPO family.
  
 0.707
tfr2
Transferrin receptor 2.
  
 0.707
LOC100695592
Transferrin receptor protein 1.
  
 0.707
I3KSH9_ORENI
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
  
 
 0.647
mis12
MIS12 kinetochore complex component.
    
   0.630
LOC100694811
Hemopexin a.
   
 0.576
LOC100702432
Uncharacterized protein.
   
 0.545
srprb
SRP receptor subunit beta.
 
      0.536
ube2i
Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.
      
 0.523
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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