Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
G3bp1GTPase activating protein (SH3 domain) binding protein 1. (500 aa)    
Predicted Functional Partners:
caprin1
Cell cycle associated protein 1b.
   
 
 0.920
I3JFY6_ORENI
Cell cycle associated protein 1a.
   
 
 0.920
usp10
Ubiquitin carboxyl-terminal hydrolase.
   
 
 0.909
I3KAX8_ORENI
Ataxin 2.
   
 
 0.874
nufip2
Nuclear FMR1 interacting protein 2.
   
 
 0.830
fmr1
Fragile X mental retardation 1.
   
 
 0.829
LOC100693655
Uncharacterized protein.
    
 0.804
UPF1
UPF1 RNA helicase and ATPase.
    
 0.804
rack1
Guanine nucleotide-binding protein subunit beta-2-like 1; Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Required for VANGL2 membrane localization, inhibits Wnt signaling and regulates cellular polarization and oriented cell division during gastrulation (By similarity); Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
   
 
 0.802
pum1
Pumilio RNA-binding family member 1.
   
 
 0.795
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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