Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lrp1bLow density lipoprotein receptor-related protein 1Bb. (4588 aa)    
Predicted Functional Partners:
Lrpap1
Low density lipoprotein receptor-related protein associated protein 1.
    
 0.955
LOC100699941
Putative apolipoprotein E.
    
 0.952
lrig1
Leucine-rich repeats and immunoglobulin-like domains 1.
   
 0.867
gulp1
GULP PTB domain containing engulfment adaptor 1a.
    
 0.864
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
     
 0.863
LOC100701980
Calreticulin.
    
 0.845
LOC100711757
Calreticulin.
    
 0.845
LOC100704618
Calreticulin.
    
 0.845
LOC100691550
PID domain-containing protein.
    
 0.831
LOC100692629
C1q domain-containing protein.
    
  0.816
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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