Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AsipAgouti domain-containing protein. (128 aa)    
Predicted Functional Partners:
mc1r
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
    
 0.999
mgrn1
Mahogunin, ring finger 1b.
      
 0.900
LOC100695984
Melanocortin 4 receptor.
    
 0.777
tyrp1
Tyrosinase related protein 1.
      
 0.775
LOC100693278
Melanocortin 5b receptor.
    
 0.745
LOC100693550
Melanocortin 2 receptor.
    
 0.728
LOC100711224
Tyrosinase-related protein 1b.
      
 0.727
Oca2
Oculocutaneous albinism II.
      
 0.686
srp14
Signal recognition particle 14.
      
 0.677
tyr
Tyrosinase.
      
 0.669
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.