Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tbc1d2TBC1 domain family, member 2. (1143 aa)    
Predicted Functional Partners:
LOC100696865
Uncharacterized protein.
    
 0.716
LOC102076290
Ras-related protein Rab-7A.
    
 0.716
I3KTW5_ORENI
NRDE-2, necessary for RNA interference, domain containing.
    
 0.640
lrrk1
Uncharacterized protein.
    
 
 0.630
wdr90
WD repeat domain 90.
    
   0.621
TBC1D13
TBC1 domain family member 13.
      
 0.593
I3JR68_ORENI
NME/NM23 family member 8; Belongs to the NDK family.
    
 
 0.580
rab31
RAB31, member RAS oncogene family.
    
 0.563
rab22a
RAB22A, member RAS oncogene family.
    
 0.563
Cfap126
Protein Flattop.
   
   0.551
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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