Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pck1Phosphoenolpyruvate carboxykinase 1 (soluble). (672 aa)    
Predicted Functional Partners:
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.964
LOC100711605
Malate synthase-like.
     
 0.957
pdhb
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
     
 0.948
cs
Citrate synthase; Belongs to the citrate synthase family.
   
 
 0.947
LOC100711978
Malate dehydrogenase.
  
 
 0.942
LOC100706997
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
     
 0.942
LOC100711262
Malate dehydrogenase, cytoplasmic isoform X2.
  
 
 0.942
mdh2
Malate dehydrogenase.
    
 0.940
LOC100705311
Aspartate aminotransferase.
     
 0.937
LOC100699677
Enolase 3, (beta, muscle).
     
 0.936
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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