Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mrasMuscle RAS oncogene homolog. (208 aa)    
Predicted Functional Partners:
shoc2
SHOC2 leucine rich repeat scaffold protein.
    
 0.992
I3JW49_ORENI
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.971
pik3cd
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.969
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.969
Pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
   
 0.969
Rin1
Si:ch211-168d1.3.
    
 0.959
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
    
 0.956
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2.
    
 0.955
braf
B-Raf proto-oncogene serine/threonine-protein kinase.
    
 0.954
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
    
 0.954
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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