Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pth2rParathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (551 aa)    
Predicted Functional Partners:
Pth2
Parathyroid hormone 2.
    
 0.992
ENSONIP00000058414
Parathyroid hormone 1a.
   
 0.982
LOC109202892
Parathyroid hormone.
     
 0.937
pth1r
Parathyroid hormone 1 receptor a; Belongs to the G-protein coupled receptor 2 family.
     
  0.916
LOC100691226
Parathyroid hormone 1 receptor b; Belongs to the G-protein coupled receptor 2 family.
     
  0.916
LOC100702054
Guanine nucleotide binding protein (G protein), beta 5b.
    
  0.832
LOC100695768
Guanine nucleotide binding protein (G protein), beta polypeptide 3b.
    
  0.832
LOC100691200
Guanine nucleotide binding protein (G protein), beta polypeptide 3a.
    
  0.832
ENSONIP00000080600
annotation not available
     
 0.824
I3J1D3_ORENI
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.818
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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