Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
I3JA90_ORENISodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (669 aa)    
Predicted Functional Partners:
slc8b1
Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
   
 
 0.628
I3K395_ORENI
Sodium/potassium-transporting ATPase subunit alpha.
    
 
 0.529
LOC100712391
Sodium/potassium-transporting ATPase subunit alpha.
    
 
 0.529
LOC100707930
Sodium/potassium-transporting ATPase subunit alpha.
    
 
 0.529
ATP4A
Sodium/potassium-transporting ATPase subunit alpha.
    
 
 0.526
LOC100699477
Sodium/potassium-transporting ATPase subunit alpha.
    
 
 0.526
LOC100694151
Sodium/potassium-transporting ATPase subunit alpha.
    
 
 0.525
LOC100692262
Sodium/potassium-transporting ATPase subunit alpha.
    
 
 0.523
tmco3
Transmembrane and coiled-coil domains 3.
   
 
 0.507
setd2
SET domain containing 2, histone lysine methyltransferase.
      
 0.494
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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