Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
I3JAF1_ORENIPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (270 aa)    
Predicted Functional Partners:
LOC100705642
Lysyl oxidase-like 1.
    
 0.594
LOC100695265
Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
    
  0.533
F2RL3
F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
 0.523
LOC100694080
Transmembrane serine protease 4a; Belongs to the peptidase S1 family.
  
 
 0.522
LOC102078018
Coagulation factor II (thrombin) receptor-like 2.
    
  0.514
casp7
Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.502
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
  0.492
parp4
Poly [ADP-ribose] polymerase.
   
 
 0.491
LOC100702139
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.490
Parp2
Poly [ADP-ribose] polymerase.
   
 
  0.487
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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