Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
igfbp5Insulin-like growth factor binding protein 5a. (266 aa)    
Predicted Functional Partners:
I3KMU3_ORENI
Insulin-like growth factor 1.
   
 0.926
I3KAU3_ORENI
Insulin-like growth factor 2b.
   
 0.775
igfals
Shisa family member 9b.
    
 0.759
pappa
Pregnancy-associated plasma protein A, pappalysin 1a.
    
 0.742
I3KYZ4_ORENI
LRRCT domain-containing protein.
    
 0.603
I3J1Y4_ORENI
FAM20C golgi associated secretory pathway kinase a.
    
  0.496
LOC100706789
Fam20C domain-containing protein.
    
  0.496
LOC100707581
Tyrosine-protein kinase receptor.
   
 
 0.494
htra1
HtrA serine peptidase 1b.
      
 0.451
ghr1
Growth hormone receptor a.
   
  
 0.431
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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