Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
I3JAK0_ORENIUncharacterized protein. (364 aa)    
Predicted Functional Partners:
rab27b
RAB27B, member RAS oncogene family.
   
 0.799
LOC100706684
Uncharacterized protein.
   
 0.799
rab27a
RAB27A, member RAS oncogene family.
   
 0.799
ENSONIP00000000682
Intersectin 2a.
     
 0.557
I3KKD0_ORENI
Intersectin 2b.
     
 0.557
LOC100695826
Rab-GAP TBC domain-containing protein.
     
  0.541
tbc1d10b
TBC1 domain family, member 10b.
     
  0.541
Tbc1d10a
TBC1 domain family, member 10Aa.
     
  0.541
lhfpl2
LHFPL tetraspan subfamily member 2a.
     
 0.525
RIMS2
Regulating synaptic membrane exocytosis 2.
     
 0.474
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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