STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100699836RAB38b, member of RAS oncogene family. (218 aa)    
Predicted Functional Partners:
gak
Cyclin G associated kinase.
    
 
 0.733
Vti1a
Vesicle transport through interaction with t-SNAREs 1A.
      
 0.655
ankrd27
Ankyrin repeat domain 27 (VPS9 domain).
    
 
 0.618
rabggta
Rab geranylgeranyltransferase subunit alpha.
    
 0.604
LOC100690604
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.603
LOC100705920
Leukotriene A4 hydrolase.
      
 0.585
hps1
HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.
     
 0.509
ptar1
Protein prenyltransferase alpha subunit repeat containing 1.
    
 0.506
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6.
    
 
 0.500
prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
      
 0.480
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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