STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NplN-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); Belongs to the DapA family. (270 aa)    
Predicted Functional Partners:
gne
Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase.
    
 0.926
LOC100696106
N-acetylneuraminic acid synthase a.
     
 0.905
LOC100695847
AFP-like domain-containing protein.
     
 0.905
ENSONIP00000070193
Sialic acid synthase isoform X1.
     
 0.905
renbp
Renin binding protein.
   
 
  0.902
gclc
Glutamate-cysteine ligase, catalytic subunit.
   
 0.660
enosf1
Enolase superfamily member 1.
      
 0.491
grhpr
Glyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.448
akr7a2
Aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase).
  
 0.433
LOC100712186
Zgc:136493; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.431
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: medium (42%) [HD]