Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NplN-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); Belongs to the DapA family. (270 aa)    
Predicted Functional Partners:
LOC100691152
N-acylneuraminate/3-deoxy-D-glycero-D-galacto-nononate cytidylyltransferase.
   
 
 0.923
LOC100707770
Serine--pyruvate aminotransferase.
   
 
 0.922
LOC100695998
Serine--pyruvate aminotransferase.
   
 
 0.922
grhpr
Glyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.921
I3JBB5_ORENI
Glyoxylate reductase/hydroxypyruvate reductase a; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.918
Nanp
N-acetylneuraminic acid phosphatase.
   
 
 0.918
LOC100705311
Aspartate aminotransferase.
   
 
 0.916
hao1
Hydroxyacid oxidase (glycolate oxidase) 1.
   
 
 0.902
hao2
Hydroxyacid oxidase 2 (long chain).
   
 
 0.902
gne
Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase.
    
 0.898
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.