STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VAV3Vav guanine nucleotide exchange factor 3. (864 aa)    
Predicted Functional Partners:
RAC2
Rac family small GTPase 2.
   
 0.961
LOC100696401
Ras-related C3 botulinum toxin substrate 1-like.
   
 0.961
RAC1
Rac family small GTPase 1.
   
 0.961
grb2
Growth factor receptor-bound protein 2b.
    
 0.843
LOC100693657
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
    
0.772
LOC100690473
Phosphatidylinositol 3-kinase regulatory subunit gamma b.
    
0.772
LOC100710015
Uncharacterized protein.
    
0.772
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
0.772
I3K4E0_ORENI
Uncharacterized protein.
    
0.768
I3KQM2_ORENI
Phosphoinositide-3-kinase, regulatory subunit 3a (gamma).
    
0.768
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.