Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fkbp8Peptidylprolyl isomerase. (403 aa)    
Predicted Functional Partners:
LOC100691403
Tax1 (human T-cell leukemia virus type I) binding protein 1b.
    
 0.952
Prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.943
I3J608_ORENI
NBR1 autophagy cargo receptor b.
    
 0.941
nbr1
NBR1 autophagy cargo receptor a.
    
 0.941
huwe1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
    
 0.938
tomm70
Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae).
   
 
 0.937
optn
Optineurin.
    
 0.937
calcoco2
SKICH domain-containing protein.
    
 0.937
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
   
 0.936
gabarap
Gamma-aminobutyric acid receptor-associated protein.
   
 
 0.935
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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