Ell protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Ell

Elongation factor RNA polymerase II. (677 aa)

Predicted Functional Partners:

eaf1

0.919

aff4

0.883

eaf2

0.880

ice2

0.837

I3JL78_ORENI

0.802

cdk9

0.775

polr2c

0.754

polr2b

0.743

LOC100694205

0.724

I3JUU4_ORENI

0.724

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ell	I3JL78_ORENI	ENSONIP00000006003	ENSONIP00000080793	Elongation factor RNA polymerase II.	Uncharacterized protein.	0.802
Ell	I3JUU4_ORENI	ENSONIP00000006003	ENSONIP00000076027	Elongation factor RNA polymerase II.	MLLT1 super elongation complex subunit a.	0.724
Ell	LOC100694205	ENSONIP00000006003	ENSONIP00000023922	Elongation factor RNA polymerase II.	MLLT3 super elongation complex subunit.	0.724
Ell	aff4	ENSONIP00000006003	ENSONIP00000010618	Elongation factor RNA polymerase II.	AF4/FMR2 family, member 4.	0.883
Ell	cdk9	ENSONIP00000006003	ENSONIP00000015861	Elongation factor RNA polymerase II.	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	0.775
Ell	eaf1	ENSONIP00000006003	ENSONIP00000057237	Elongation factor RNA polymerase II.	ELL associated factor 1.	0.919
Ell	eaf2	ENSONIP00000006003	ENSONIP00000021510	Elongation factor RNA polymerase II.	ELL associated factor 2.	0.880
Ell	ice2	ENSONIP00000006003	ENSONIP00000019246	Elongation factor RNA polymerase II.	Interactor of little elongator complex ELL subunit 2.	0.837
Ell	polr2b	ENSONIP00000006003	ENSONIP00000000084	Elongation factor RNA polymerase II.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.743
Ell	polr2c	ENSONIP00000006003	ENSONIP00000030110	Elongation factor RNA polymerase II.	Polymerase (RNA) II (DNA directed) polypeptide C.	0.754
I3JL78_ORENI	Ell	ENSONIP00000080793	ENSONIP00000006003	Uncharacterized protein.	Elongation factor RNA polymerase II.	0.802
I3JL78_ORENI	I3JUU4_ORENI	ENSONIP00000080793	ENSONIP00000076027	Uncharacterized protein.	MLLT1 super elongation complex subunit a.	0.874
I3JL78_ORENI	LOC100694205	ENSONIP00000080793	ENSONIP00000023922	Uncharacterized protein.	MLLT3 super elongation complex subunit.	0.874
I3JL78_ORENI	aff4	ENSONIP00000080793	ENSONIP00000010618	Uncharacterized protein.	AF4/FMR2 family, member 4.	0.744
I3JL78_ORENI	cdk9	ENSONIP00000080793	ENSONIP00000015861	Uncharacterized protein.	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	0.970
I3JL78_ORENI	eaf1	ENSONIP00000080793	ENSONIP00000057237	Uncharacterized protein.	ELL associated factor 1.	0.918
I3JL78_ORENI	eaf2	ENSONIP00000080793	ENSONIP00000021510	Uncharacterized protein.	ELL associated factor 2.	0.788
I3JL78_ORENI	polr2b	ENSONIP00000080793	ENSONIP00000000084	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.666
I3JL78_ORENI	polr2c	ENSONIP00000080793	ENSONIP00000030110	Uncharacterized protein.	Polymerase (RNA) II (DNA directed) polypeptide C.	0.673
I3JUU4_ORENI	Ell	ENSONIP00000076027	ENSONIP00000006003	MLLT1 super elongation complex subunit a.	Elongation factor RNA polymerase II.	0.724