Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC112848065Zgc:171929. (280 aa)    
Predicted Functional Partners:
sdhaf1
Succinate dehydrogenase assembly factor 1, mitochondrial.
      
 0.677
nsun2
NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
      
 0.618
ubr3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
    
 
 0.503
mrpl24
Mitochondrial ribosomal protein L24.
      
 0.487
snx6
Sorting nexin; Involved in several stages of intracellular trafficking.
      
 0.480
snx5
Sorting nexin; Involved in several stages of intracellular trafficking.
      
 0.480
PRADC1
Protease associated domain containing 1.
      
 0.454
Prodh2
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
      
 0.444
LOC100697817
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
      
 0.444
LOC100695866
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
      
 0.444
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (22%) [HD]