Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rnf20E3 ubiquitin protein ligase. (1031 aa)    
Predicted Functional Partners:
leo1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.895
cdc73
Ro60, Y RNA binding protein.
   
 0.895
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component.
    
 0.887
setd2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.886
LOC100696120
WW domain-containing protein.
   
 0.875
wac
WW domain containing adaptor with coiled-coil a.
   
 0.875
ube2b
Ubiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.
    
 0.861
LOC100710794
Ubiquitin-conjugating enzyme E2 A.
    
 0.861
ube2a
Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.861
rps27a
Ribosomal protein S27a.
   
 0.858
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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