STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3JBB5_ORENIGlyoxylate reductase/hydroxypyruvate reductase a; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)    
Predicted Functional Partners:
LOC100707770
Serine--pyruvate aminotransferase.
  
 
 0.969
LOC100695998
Serine--pyruvate aminotransferase.
  
 
 0.969
glyctk
Glycerate kinase.
 
 
 0.968
hao1
Hydroxyacid oxidase (glycolate oxidase) 1.
  
 
 0.942
hao2
Hydroxyacid oxidase 2 (long chain).
  
 
 0.942
hoga1
4-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family.
  
 
 0.940
hyi
Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.
  
 
 0.924
pgp
Phosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily.
  
 
 0.923
LOC100710767
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 0.920
grhpr
Glyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 
0.901
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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