Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Spock1SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1. (479 aa)    
Predicted Functional Partners:
adam10
Uncharacterized protein.
     
 0.646
sparc
Secreted protein, acidic, cysteine-rich (osteonectin).
   
  
 0.582
GUCY1A2
Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
      
 0.573
nuak1
NUAK family, SNF1-like kinase, 1b.
   
  
 0.571
mmp15
Matrix metallopeptidase 15b.
    
 0.562
LOC100695964
Matrix metallopeptidase 14b (membrane-inserted).
    
 0.562
serpina10
Si:ch1073-416d2.3; Belongs to the serpin family.
      
 0.560
I3KRB5_ORENI
AT rich interactive domain 1B (SWI1-like).
      
 0.554
LOC100702284
TIMP metallopeptidase inhibitor 2b.
     
  0.553
timp2
TIMP metallopeptidase inhibitor 2a.
     
  0.553
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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