Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ak2Adenylate kinase 2; Belongs to the adenylate kinase family. (250 aa)    
Predicted Functional Partners:
ENSONIP00000016918
Adenylate kinase 9.
   
0.943
ak6
Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.
   
 
 0.932
LOC100703020
Nucleoside diphosphate kinase.
  
 0.927
AK1
Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
  
0.923
aprt
Adenine phosphoribosyltransferase.
  
 0.915
ntpcr
Nucleoside-triphosphatase, cancer-related.
     
 0.911
LOC100693415
Adenosine kinase a.
  
 0.902
ADK
Adenosine kinase.
  
 0.902
LOC100696772
NME/NM23 nucleoside diphosphate kinase 2a; Belongs to the NDK family.
  
 0.898
PDE7B
Phosphodiesterase.
     
 0.897
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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