Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ARHGEF17Rho guanine nucleotide exchange factor (GEF) 17. (2748 aa)    
Predicted Functional Partners:
LOC100691030
Uncharacterized protein LOC100691030.
     
  0.808
rell1
RELT like 1.
     
  0.795
tbrg1
Transforming growth factor beta regulator 1.
   
  
 0.730
sting1
Stimulator of interferon genes protein.
   
 0.673
arhgef12
Rho guanine nucleotide exchange factor (GEF) 12a.
   
 0.663
tsku
Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis).
   
  
 0.646
p2ry2
Purinergic receptor P2Y2.
      
 0.644
Rasl12
Ras-like protein family member 12 isoform X1.
    
  0.615
acer3
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
      
 0.611
rai14
Retinoic acid induced 14.
      
 0.568
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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